Does being overweight make asthma worse?
Asthma is a chronic respiratory condition that affects millions of people worldwide. It is characterized by inflammation and narrowing of the airways, leading to symptoms such as coughing, wheezing, shortness of breath, and chest tightness. While there are various factors that can contribute to the severity of asthma, one question that often arises is whether being overweight makes asthma worse. This article aims to explore this topic and provide insights into the potential link between obesity and asthma.
Obesity and Inflammation
Research has shown that obesity is associated with chronic low-grade inflammation throughout the body. This systemic inflammation can have a significant impact on various organs and systems, including the respiratory system. In the case of asthma, the presence of inflammation can exacerbate airway narrowing and worsen symptoms.
Adipose Tissue and Leukotrienes
One of the primary sources of inflammation in obesity is adipose tissue, which is the body’s fat storage. Adipose tissue produces a variety of inflammatory substances, including leukotrienes. Leukotrienes are potent mediators of inflammation and play a crucial role in the pathophysiology of asthma. Increased levels of leukotrienes in overweight individuals can lead to more severe asthma symptoms and exacerbations.
Obesity and Airway Remodeling
Obesity and Medication ResistanceConclusion